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Ming Xu, Ph.D.
Professor of Anesthesia and Critical Care
Training:
B.S. - 1982
Peking University - chemistry

Ph.D. - 1989
University of Texas Southwestern Medical Center, Dallas - molecular biology
Academic Interests:
Basic research in the function of the brain's dopamine system and drug addiction.
Representative Publications :
Zhang J, Zhang D, McQuade JM, Behbehani M, Tsien J, Xu M. C-fos is a genetic regulator in cellular mechanisms mediating neuronal excitability and survival. Nat Genet 30: 416-420, 2002

Zhang D, Zhang L, Lou D, Nakabeppu Y, Zhang J, Xu M. The dopamine D1 receptor is a critical mediator for cocaine-induced gene expression. J Neurochem 82:1453-1464, 2002

Zhang J, Dong M, Li L, Pathre P, Fan Y, Dong J, Lou D, Wells J, Olivares-Villagom D, Van Kaer L, Wang X, Xu M. Endonuclease G is required for normal apoptosis and early embryogenesis in mice. Proc Natl Acad Sci USA 100:15782-15787, 2003

Zhang L, Lou D, Jiao H, Zhang D, Wang X, Ying X, Zhang J, Xu M. Cocaine-induced intracellular signaling and gene expression are oppositely regulated by the dopamine D1 and D3 receptors. J Neurosci 24:3344-3354, 2004

Zhang D, Zhang L, Tang Y, Zhang Q, Lou D, Sharp FR, Zhang J, Xu M. Repeated cocaine administration induces gene expression changes through the dopamine D1 receptors. Neuropsychopharmacology 30:1443-1454, 2005

Zhang J, Zhang L, Jiao H, Zhang Q, Zhang D, Lou D, Katz J, Xu M. C-fos facilitates acquisition and extinction of cocaine-induced persistent change. J Neurosci 26:13287-13296, 2006

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